1.

You have a choice to make. And I don't want to rush you into making the decision before you're ready. This morning I was going to come over... I was going to say... what I wanted to say was... But now all I can say is that... I'm in love with you. I've been in love with you for, ever. I'm a little late, I know I'm a little late in telling you that. I just, I just want you to take your time, you know. Take all the time you need, because you have a choice to make. And when I had a choice to make, I chose wrong. (Grey's Anatomy)

2.

Communication. It's the first thing we really learn in life. Funny thing is, once we grow up, learn our words and really start talking the harder it becomes to know what to say. Or how to ask for what we really need. (Grey's Anatomy)

3.

You don't open yourself up- to anyone. Sometimes I think it's charming and she's different, she's not like other women. The simple fact is that you have never let me in. What? You think that it's gonna make a good marriage? 'Cause I don't. I don't want you to marry me because you're placating me. It doesn't interest me. It doesn't interest me at all." (Grey's Anatomy)

4.

You know how when you were a little kid and you believed in fairy tales. That fantasy of what your life would be, white dress, prince charming who would carry you away to a castle on a hill. You would lie in bed at night and close your eyes and you had complete and utter faith. Santa Claus, the Tooth Fairy, Prince Charming, they were so close you could taste them. But eventually you grow up, one day you open your eyes and the fairy tale disappears. Most people turn to the things and people they can trust. But the thing is its hard to let go of that fairy tale entirely cause almost everyone has that smallest bit of hope, of faith, that one day they will open their eyes and it will come true. (Grey's Anatomy)

5.

It was a Thursday morning. You were wearing that ratty little “Dartmouth” t-shirt you look so good in, the one with the hole in the back of the neck. You’d just washed your hair and you smelled like some kind of… flower. I was running late for surgery. You said you were going to see me later, and you leaned to me, put your hand on my chest, and you kissed me. Soft. It was quick; kind of like a habit. You know, like we’d do it everyday for the rest of our lives. And you went back to reading the newspaper and I went to work. That was the last time we kissed. (Grey's Anatomy) 

7.

At the end of the day, when it comes down to it, all we really want is to be close to somebody. So this thing, where we all keep our distance and pretend not to care about each other, is usually a load of bull. So we pick and choose who we want to remain close to, and once we've chosen those people, we tend to stick close by. No matter how much we hurt them, the people that are still with you at the end of the day - those are the ones worth keeping. And sure, sometimes close can be too close. But sometimes, that invasion of personal space, it can be exactly what you need. (Grey's Anatomy)

8.

You don't get to call me a whore. When I met you, I thought I had met the person I would spend then rest of my life with. I was done. So all the boys, and all the bars, and all the obvious daddy issues... who cared? Because I was done. You left me. You chose her. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore. (Grey's Anatomy)

9.

For a kiss to be really good, you want it to mean something. You want it to be with someone you can't get out of your head, so that when your lips finally touch you feel it everywhere. A kiss so hot and so deep you never want to come up for air. You can't cheat your first kiss. Trust me, you don't want to. Cause when you find that right person for a first kiss, it's everything. (Grey's Anatomy)

10.

There’s an old proverb that says you can’t choose your family. You take what the fates hand you. And like them or not, love them or not, understand them or not, you cope. Then there’s the school of thought that says the family you’re born into is simply a starting point. They feed you, and clothe you, and take care of you, until you’re ready to go out into the world and find your tribe. (Grey's Anatomy)

11.

I think you can’t wait for someone to fly underneath you and save your life. I think you have to save yourself. (Grey's Anatomy)

12.

That’s how you stay alive. When it hurts so much you can’t breathe, that’s how you survive. By remembering that one day, somehow, impossibly, you won’t feel this way. It won’t hurt this much. (Grey's Anatomy)

13.

The thing people forget is how good it can feel when you finally set secrets free. Whether good or bad, at least they’re out in the open, like it or not. And once your secrets are out in the open, you don’t have to hide behind them anymore. The problem with secrets is even when you think you’re in control, you’re not. (Grey's Anatomy)

14.

You never know the biggest day of your life is the biggest day. Not until it’s happening. You don’t recognize the biggest day of your life, not until you’re right in the middle of it. The day you commit to something or someone. The day you get your heart broken. The day you meet your soul mate. The day you realize there’s not enough time, because you wanna live forever. Those are the biggest days. The perfect days. You know? (Grey's Anatomy)

15.

Okay, here it is, your choice... it's simple, her or me, and I'm sure she is really great. But Derek I love you, in a really, really big pretend to like your taste in music, let you eat the last piece of cheesecake, hold a radio over my head outside your window, unfortunate way that makes me hate you, love you. So pick me. Choose me. Love me.  (Grey's Anatomy)

16.

Pain. You just have to ride it out, hope it goes away on its on. Hope the wound that caused it heals. There are no solutions, no easy answers. You just breath deep and wait for it subside. Most of the time pain can be managed, but sometimes the pain gets you when you least expect it, hits way below the belt and doesn't let up. Pain. You just have to fight through, because the truth is you can't outrun it... And life always makes more. (Grey's Anatomy)